steve jobs pancreatic cancer

    In its announcement of the death of founder Steve Jobs, at age 56, Apple officials did not mention a specific cause of death.

    the death of Daniel J. Steve Jobs DeNoon a rare form of pancreatic cancer raises a number of questions.

    surgery for a rare form of pancreatic cancer in August 2004.

    Pancreatic cancer is notoriously lethal - there are almost as many deaths from it every year, as there are new cases. The death this week of Apple founder Steve Jobs and Nobel Prize winner Ralph Steinman unusual attention to such lesser known cancers that has actually been declining although no breakthroughs in the treatment or early detection.

    A decrease in the consumption of snuff, one of the major risk factors for disease, may be behind the drop in cases.

    Jobs lived more than seven years after being diagnosed with a neuroendocrine tumor - a less common, type of slower growth and more treatable cancer of the pancreas that Steinman guy who killed a week ago and the actor Patrick Swayze two years ago .

    Apple chief kept the details of his illness, behind a firewall and said he was cured after cancer surgery in 2004. But five years later, emaciated and having lost much weight, Jobs had a liver transplant. They said it was likely because his cancer had returned or spread.

    A liver transplant can sometimes cure the cancer that Jobs had. But if it returns, "usually one or two years," said Dr. Michael Pishvaian Georgetown University Lombardi Comprehensive Cancer Center.

    In January, Jobs announced its third and final leave of absence. He resigned in August and died on Wednesday.

    Part of what makes pancreatic cancer so deadly is that the pancreas is as vital as the heart. You can live with only one part of a liver or colon, or a single kidney or lung. However, the pancreas is a fish-shaped organ that makes digestive enzymes and insulin and other hormones that allow the body to produce energy from food.

    In the United States, cancer of the pancreas is the fourth leading cause of cancer death. About 44,030 people will be diagnosed with it and about 37,660 people die from this year in the U.S., estimates from the American Cancer Society.

    Possible symptoms include fatigue, back pain, abdominal pain, unexplained weight loss, loss of appetite, jaundice and vomiting, according to the Lustgarten Foundation, a private group that finances research on the disease.

    This cancer is often not until it is advanced or has spread, and overall survival is dismal: 20 percent after one year and only 4 percent after five years.

    However, with a neuroendocrine tumor that Jobs was like, "people can live longer, the median survival is five to eight years," said Dr. Alan Venook, a pancreatic cancer specialist at the University of California at San Francisco.

    The risk of developing pancreatic cancer is about 1 in 71, according to the cancer society. Men and blacks represent the largest number of cases and white women, possibly due to differences in smoking rates. Smokers have a risk two to three times more than the disease. Using smokeless snuff increases the risk.

    Obese people, those who do not do much exercise and diabetes are at higher risk of pancreatic cancer. Alcohol consumption may play a role: most studies have not linked to pancreatic cancer, but drinking too much can lead to diabetes and liver and pancreas that pose a risk of cancer, the cancer society says.

    The best hope for a patient is that the tumor is operable. That was the case in February 2009, when the U.S. Supreme Court Justice Ruth Bader Ginsburg was a small early-stage tumor of the pancreas removed in the Central New York's Memorial Sloan-Kettering Cancer.

    On the horizon are the treatments for immune system - the research Steinman, Nobel recipient of Rockefeller University in New York, was studying in the laboratory and treating pancreatic cancer in your account.

    The immune system has difficulty recognizing and fighting cancer because the enemy is not an invading germ, but our own cells become corrupt. Treatment called therapeutic cancer vaccines are ways to modify the cells to help the immune system to recognize the risk.

    One of these vaccines by Newlink Genetics, a small biotech company in Ames, Iowa, are now being tested for pancreatic cancer. The company's Web site says the larger study was started after a test in mid-stage indicated an improvement in survival.

    Dr. Roderich Schwarz, chief of surgical oncology at the University of Texas Southwestern Medical Center at Dallas, has enrolled a few patients in some studies of immune therapy, which have not been successful in the past.

    "Vaccines are coming along," and the adoption last year of advanced prostate cancer suggests that researchers can learn to overcome some of the drawbacks of the past, he said.

    "It's very possible that vaccines claim their territory in the treatment of these tumors difficult," said Schwarz. "It's still in development rather than the stage show".

    No specific reason was given for the death of former Apple CEO Steve Jobs, but it is well known that battled pancreatic cancer, an extremely lethal type of disease.

    November is Awareness pancreatic cancer, and here's a little about the disease of the American Cancer Society:

    + In 2011 an estimated 44.030 new cases and there are 37,660 deaths.

    + 20 percent of the population lives at least one year but less than 4 percent live more than 5 years. Catching the disease early offers the best odds.

    The causes are unknown, although +, but risk factors include age (most patients are over 55 years), being male and African-Americans, smoking, obesity, diabetes, chronic pancreatitis, or inflammation, liver cirrhosis, exposure to certain chemicals, family history.

    + There is no sure way to prevent pancreatic cancer.

    + It is difficult to detect early because the pancreas lies deep in the belly and they tend not to tumors and blood tests do not usually work early. Usually the cancer has spread by the time symptoms appear, which is why it is so deadly. Genetic testing of individuals with strong family histories may be at risk of an individual.

    + The symptoms can be confused with other problems, since they are general in nature. You can include yellowing of the eyes and skin, pain in the belly or mid-back, weight loss, fatigue, nausea, swelling of the gallbladder, blood clots and digestive problems, as it releases enzymes that break down fats and proteins in food and produces hormones like insulin that help balance blood sugar.

    + Treatments include surgery, radiation and chemotherapy. A complex called Whipple procedure can cure cancer. It is the removal of parts of the pancreas, stomach and small intestine, common bile duct and gallbladder, and some lymph nodes. Other treatments can shrink tumors or destroy cancer cells. The new screening methods are being used and also affect some medicines are being used. Clinical trials of new therapies are ongoing.

    The area hospitals have specialists who research and treatment of pancreatic cancer, including Johns Hopkins, the University of Maryland and San Jose.













































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